Anti-Filamin A antibody [EP2405Y] ab76289 from Abcam

Product Specs
ItemAnti-Filamin A antibody [EP2405Y]
CompanyAbcam
Price Supplier Page View Supplier Product Page
Catalog Numberab76289
Antibody TypePrimary
Conjugate/TagUnconjugated
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
IsotypeIgG
CloneEP2405Y
HostRabbit
Quantity10 UL, 40 UL, 100 UL
Gene NameFLNA
ValidationKnockOut Validated
ReactivityAfrican green monkey, Human, Mouse, Rat
TargetFilamin A

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(1) WTAP regulates autophagy in colon cancer cells by inhibiting FLNA through N6-methyladenosineCell Adhesion & MigrationDecember 31, 2023Liang Huang, Jinfan Shao, Xijuan Xu, Weiwen Hong, Wenfeng Yu, Shuang Zheng, Xiaogang Gevisualizer. The primary antibodies were sourced from Abcam (UK): rabbit anti-human WTAP (ab195380), FLNA (ab76289), LC3I/II (LC3B, ab51520), β-actin (ab8227), p62 (ab109012). The secondary antibody was goat anti-rabbit

(2) ULK phosphorylation of STX17 controls autophagosome maturation via FLNAJ Cell BiolJune 30, 2023Yufen Wang, Huilin Que, ChuangPeng Li, Zhe Wu, Fenglei Jian, Yuan Zhao, Haohao Tang, Yang Chen, Shuaixin Gao, Catherine C.L. Wong, et al.polyclonal anti-GFP (Cat#ab13970, Lot#GR3361051-7,RRID: AB_300798), Rabbit monoclonal anti-FLNA (Cat#ab76289, Lot#GR212664-10, RRID: AB_1523618), and Goat Anti-Chicken IgY H&L (FITC; Cat#ab46969, Lot#GR3179274-12,

(3) Transcription factor AP-2α activates RNA polymerase III-directed transcription and tumour cell proliferation by controlling expression of c-MYC and p53Journal of Biological ChemistryMarch 1, 2023Juan Wang, Qiyue Chen, Feixia Peng, Shasha Zhao, Cheng Zhang, Xiaoye Song, Deen Yu, Zhongyu Wu, Jiannan Du, Hongwei Ni, et al.electrophoresis. After that, immunoblotting was performed using antibodies against the factors, including FLNA (Ab76289, Abcam), TFAP2A (Ab108311, Abcam), HA (H9658, Sigma-Aldrich), GAPDH (RAB0101, Frdbrio), BRF1 (SC-81405,

(4) Deficiency of filamin A in smooth muscle cells protects against hypoxia‑mediated pulmonary hypertension in miceInternational Journal of Molecular MedicineJanuary 26, 2023Yaguo Zheng, Hong Ma, Yufeng Yan, Peng Ye, Wande Yu, Song Lin, Shao-Liang Chencat. no. 2586) were purchased from Cell Signaling Technology, Inc. Antibodies against FLNA (cat. no. ab76289), Ras-related C3 botulinum toxin substrate 1 (Rac1; cat. no. ab33186) and α-smooth muscle actin (α-SMA;

(5) Blood-Borne Microparticles Are an Inflammatory Stimulus in Type 2 Diabetes MellitusImmunoHorizonsJanuary 1, 2023Thom SR, Bhopale VM, Arya AK, Ruhela D, Bhat AR, Mitra N, Hoffstad O, Malay DS, Mirza ZK, Lantis JC, et al.eBioscience, San Diego, CA), anti–IL-1β (cat# ab9722; Abcam, Cambridge, MA), anti-Filamin Ab (cat# ab76289; Abcam), anti–IL-18 (cat# ab243091; Abcam), anti-myeloperoxidase (anti-MPO; cat# HM1051PE-100; Hycult Biotech

(6) Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factorsCellular and molecular life sciences : CMLSAugust 1, 2022Liu L, Kryvokhyzha D, Rippe C, Jacob A, Borreguero-Muñoz A, Stenkula KG, Hansson O, Smith CWJ, Fisher SA, Swärd K.Biosciences, 610,418), SLMAP (Millipore Sigma, HPA002357), ACTN1 (Sigma-Aldrich, HPA006035), FLNA (Abcam, ab76289), TPM1 (Cell Signaling Technology, 3910S), CALD1 (Cell Signaling Technology, 12503S), VCL (Cell Signaling Technology

(7) Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteinsProceedings of the National Academy of Sciences of the United States of AmericaApril 26, 2022Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, et al.proteins (Merck, clone FK2, 04-263), anti-beta actin (Merck, clone 4, MAB1505), anti-Filamin A (Abcam, ab76289), anti-ZYX (kindly provided by Prof. Benjamin Geiger, made by Antibody Production Laboratory of the

(8) The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sacNature CommunicationsDecember 1, 2021Lei Chen et al.2 (Santa Cruz sc-373966, 1 : 200), Laminin γ-2 (Santa Cruz sc-28330, 1 : 200), and Filamin A (Abcam ab76289, 1 : 500). Blocking reagents and secondary antibodies were used according to the manufacturer’s protocol

(9) The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomesNature communicationsNovember 12, 2021Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H.antibodies were used: Phafin2 antibody, Sigma-Aldrich (HPA024829) (WB, 1:500). FilaminA antibody, Abcam (ab76289) (WB, 1:1000). Atto-488 conjugated anti-GFP nanobody, Chromotek (gba488) (IF, 1:100). γ-Tubulin antibody,

(10) Hippocampus chronic deep brain stimulation induces reversible transcript changes in a macaque model of mesial temporal lobe epilepsyChinese Medical JournalAugust 5, 2021Ning Chen, Jian-Guo Zhang, Chun-Lei Han, Fan-Gang Mengwith primary antibodies against: Col1a2 (1:500; Abcam/ab96723, Cambridge, MA, USA), Flna (1:100; Abcam/ab76289, Cambridge, MA, USA), Itgb1 (1:500; Abcam/ab179471, Cambridge, MA, USA) and glyceraldehyde-3-phosphate

(11) Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in MiceArteriosclerosis, Thrombosis, and Vascular BiologyMay 5, 2021Latha Muniappan et al.(Abcam, catalog No: ab39170), calpain-2 (Abcam, catalog No: ab39165), filamin A (Abcam, catalog No: ab76289), talin (Abcam, catalog No: ab71333), α-spectrin (Millipore, catalog No: MAB1622), ILK-1 (Cell Signaling,

(12) Neo-Fs Index: A Novel Immunohistochemical Biomarker Panel Predicts Survival and Response to Anti-Angiogenetic Agents in Clear Cell Renal Cell CarcinomaCancersMarch 10, 2021Kim J, Park JY, Shin SJ, Lim BJ, Go H.anti-KMT2D antibody (rabbit, 1:100; NBP1-89123; Novus Biologicals), anti-filamin A antibody (mouse, 1:400; ab76289, clone EP1238Y; Abcam), anti-PTEN antibody (rabbit, 1:100; 138G6; Cell Signaling, Danvers, MA, USA),

(13) Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesisCell death & diseaseFebruary 10, 2021Lou Y, Xu J, Zhang Y, Zhang W, Zhang X, Gu P, Zhong H, Wang H, Lu J, Han B.in TBST solution with 5% skim milk as indicated): anti-LANCL2 (1:500, ab88860), anti-FLNA (1:1000, ab76289), anti-FASN (1:1000, ab128870), anti-TRIM25 (1:1000, ab167154), anti-YWHAB (1:1000, ab32560) (all from

(14) Downregulation of Filamin a Expression in the Aorta Is Correlated With Aortic DissectionFrontiers in cardiovascular medicineJanuary 1, 2021Chen Y, Wei X, Zhang Z, He Y, Huo B, Guo X, Feng X, Fang ZM, Jiang DS, Zhu XH.visualization using a ChemiDocTM XRS+ system (Bio-Rad). The antibodies used in this study included FLNA (ab76289, Abcam), FLNB (GTX101206, GeneTex), FLNC (ab180941, Abcam), HA (H3663, Sigma), Flag (F1084, Sigma),

(15) Role and mechanism of FLNa and UCP2 in the development of cervical cancerOncology reportsDecember 1, 2020Wang A, Liu L, Yuan M, Han S, You X, Zhang H, Lei F, Zhang Y.Abcam); anti-UCP2 (1:100; cat. no. 11081-1-AP; ProteinTech Group, Inc.) and anti-FLNa (1:100; cat. no. ab76289; Abcam). The antibodies were used to detect UCP2 and FLNa expression in different CC cell lines. The

(16) Influenza A Virus Nucleoprotein Activates the JNK Stress-Signaling Pathway for Viral Replication by Sequestering Host Filamin A ProteinFrontiers in MicrobiologySeptember 25, 2020Anshika Sharma, Jyoti Batra, Olga Stuchlik, Matthew S. Reed, Jan Pohl, Vincent T. K. Chow, Suryaprakash Sambhara, Sunil K. Lalmonoclonal antibody (SC-73614: SCB), anti-GFP antibody (SC-9996: SCB), anti-FLNA monoclonal antibody (AB76289: Abcam, Cambridge, United Kingdom), anti-FLNA monoclonal antibody (SC-17749: SCB), anti-phospho-P53

(17) Progression of Fetal Brain Lesions in Tuberous Sclerosis ComplexFrontiers in NeuroscienceAugust 21, 2020Antoinette Bernabe Gelot, Alfonso RepresaCell Signaling Technology, Danvers). Finally, we also used rabbit anti FLNA (1:250 clone EP2405Y; Abcam ab76289), as a recent study reported that filamin A antibodies stained Giant/Balloon cells and dysmorphic neurons

(18) Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivatorsAmerican journal of physiology. Cell physiologyDecember 1, 2019Swärd K, Krawczyk KK, Morén B, Zhu B, Matic L, Holmberg J, Hedin U, Uvelius B, Stenkula K, Rippe C.610418 from BD Biosciences; SORBS1: ab224129 from Abcam; SLMAP: HPA002357 from Sigma-Aldrich; FLNA: ab76289 from Abcam; LAMC1, sc-5584 from Santa Cruz Biotechnology; MCAM: SAB5600062 from SigmaAldrich; CFL2:

(19) Overexpression of calpain‑1 predicts poor outcome in patients with colorectal cancer and promotes tumor cell progression associated with downregulation of FLNAOncology ReportsApril 16, 2019Changzhao Xu, Xiaoxiao Yu, Yuesheng Zhu, Zhenzhai Cai, Lingmin Yu, Ying Lin, Hejie Yu, Zhanxiong Xue, Lingling Zhou(rabbit monoclonal; cat. no. ab108400; Abcam; dilution 1:150) or anti‑FLNA (rabbit monoclonal; cat. no. ab76289; Abcam; dilution 1:800) antibodies overnight at 4˚C in a humid environment followed by streptavidin‑peroxidase‑conjugated

(20) Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During MitosisCerebral CortexMarch 1, 2019Gewei Lian, Timothy Wong, Jie Lu, Jianjun Hu, Jingping Zhang, Volney Sheenanti-Flag antibody (Sigma Cat: F3165), and detect by Western blot with anti-FLNA antibody (Abcam Cat: ab76289). For RhoA activation assays, WT and null FlnA neural progenitors were plated to 10 ug/ml laminin-coated

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Anti-Filamin A antibody [EP2405Y] from Abcam

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Anti-Filamin A antibody [EP2405Y] from Abcam

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